Unidad de Patología Experimental


Dr. Rogelio Hernández Pando

(55) 5487-0900 Ext.7126
rogelio.hernandezp@incmnsz.mx

GRADO ACADÉMICO: Doctor en Investigación Biomédica Básica
CATEGORÍA: Investigador en Ciencias Medicas F
SISTEMA NACIONAL DE INVESTIGADORES Nivel III

 

LINEAS DE INVESTIGACIÓN

Patología experimental.

Inmunopatología de la tuberculosis.


PUBLICACIONES RELEVANTES DE LOS ULTIMOS 5 AÑOS

Silva-Sánchez A, Meza-Pérez S, Flores-Langarica A, Donis-Maturano L, Estrada-García I, Calderón-Amador J, Hernández-Pando R, Idoyaga J, Steinman RM, Flores-Romo L. ESAT-6 Targeting to DEC205+ Antigen Presenting Cells Induces Specific-T Cell Responses against ESAT-6 and Reduces Pulmonary Infection with Virulent Mycobacterium tuberculosis. PLoS One. 2015 Apr 27;10(4):e0124828. doi: 10.1371/journal.pone.0124828. eCollection 2015.

Rivas-Santiago B, Rivas-Santiago C, Sada E, Hernández-Pando R. Prophylactic Potential of Defensins and L-isoleucine in Tuberculosis Household Contacts: an experimental model. Immunotherapy 2015; 7 (3): 207-213.

Bini EI, Mata D, Marquina B, Barrios Payan J, Colucci DG, Francisco Cruz A, Zatarain ZL, Alfonseca E, Romano M, Bottasso O, Hernández-Pando R. The influence of sex steroid hormones in the immunopathology of experimental pulmonary tuberculosis. PlosOne 2014; 9(4): e93831. doi:10.1371/journal.pone.0093831.

Valdés I, Montoro E, Mata-Espinoza D, Asin O, Barrios-Payan J, Francisco Cruz A, Valdivia JA, Hernández-Pando R. Virulence, immunogenicity and protection conferred by Mycobacterium ´habana´ in a murine model of pulmonary tuberculosis. Tuberculosis (Edinburgh) 2014 Jan; 94(1):65-72.

González-Pérez M, Mariño-Ramírez L, Parra-López C, Murcia M, Marquina B, Mata-Espinoza D, Rodriguez-Míguez Y, Baay-Guzman G, Huerta-Yepez S, Hernandez-Pando R. Virulence and immune response induced by Mycobacterium avium complex strains in a model of progressive pulmonary tuberculosis and subcutaneous infection in BALB/c mice. Infection and Immunity 2013, 81(11):4001. DOI: 10.1128/IAI.00150-13.

Olivares N; Marquina B; Mata D; Zatarain-Borroso Z; Espitia Clara; Estrada Garcia I; Parada C; Collin M; Rook G, Hernandez Pando R. The protective effect of immunoglobulin in murine tuberculosis is dependent on IgG glycosylation. Pathogens and Disease 2013, Dec;69(3):176-83. doi: 10.1111/2049-632X.12069.

Rivas-Santiago B, Castañeda-Delgado JE, Rivas Santiago CE, Waldbrook M, González-Curiel I, León–Contreras JC, Enciso-Moreno A, del Villar V, Méndez-Ramos J, Hancock R, Hernandez-Pando R. Ability of Innate Defence Regulator Peptides IDR-1002, IDR-HH2 and IDR-1018 to protect against Mycobacterium tuberculosis infections in animal models. PlosOne 2013; 8(3):e59119. doi: 10.1371/journal.pone.0059119. Epub 2013 Mar 21.

Rodríguez JE, Ramírez A, Salas-Rangel LP, Helguera-Repetto C, Gonzalez-y-Merchand JA, Soto CY and Hernández-Pando R. Transcription of Genes involved in Sulfolipid and Polyacyltrehalose Biosynthesis of Mycobacterium tuberculosis in Experimental Latent Tuberculosis Infection. PlosOne 2013; 8(3):e58378. doi: 10.1371/journal.pone.0058378. Epub 2013 Mar 5.

Francisco Cruz A, Mata Espinoza D, Xing Z, Hernandez Pando R. Immunotherapeutic effects of recombinant adenoviruses encoding GM-CSF in experimental pulmonary tuberculosis. Clinical and Experimental Immunology. 2013 Mar; 171(3):283-97.

Rivas-Santiago B, Rivas Santiago C, Castañeda-Delgado J, León–Contreras J, Hancock R, Hernandez-Pando R. Activity of LL-37, CRAMP and antimicrobial peptide-derived compounds E2, E6, and CP26 against Mycobacterium tuberculosis. International Journal of Antimicrobial Agents. 2013: 41: 143-148.

Barrios Payán J, Saqui-Salces M, Mangalakumary J, Alcantara Vazquez A, Castañón Arreola M, Rook G, Hernández Pando R. Extrapulmonary locations of Mycobacterium Tuberculosis DNA during latent infection. Journal of Infectious Diseases 2012; Oct 206 (8): 1194-205.

Rivas-Santiago C, Rivas-Santiago B, Aguilar León D, Castañeda-Delgado J, Hernández Pando R. Induction of β-Defensins by L-isoleucine as novel immunotherapy in experimental murine tuberculosis. Clinical and Experimental Immunology 2011, 164: 80-89.
Unidad de Patología Experimental